TY - JOUR AU - Djebar, Alia AU - Rouabhi, Rachid AU - Berrebbah, Houria AU - Djebar, Mohammed Reda PY - 2023/01/10 Y2 - 2024/03/29 TI - Assessment of wastewater toxicity from the pharmaceutical industry of salicylic acid and paracetamol on the roots of a plant species: Phaseolus vulgaris JF - Journal of Biological Studies JA - JBS VL - 5 IS - 5 SE - Articles DO - 10.62400/jbs.v5i5.7375 UR - https://onlinejbs.com/index.php/jbs/article/view/7375 SP - 714-725 AB - <p>Pharmaceutical compounds are currently a group of emerging environmental contaminants<br>where their presence is reported in all ecosystems (water, soil, etc.). Their effects often result<br>in strong metabolic disturbances which affect all vital functions of organisms, including plants<br>which are non-target species. During their development, plants can absorb and accumulate<br>many xenobiotics, including pharmaceutical compounds that are able to cross the root walls.<br>In order to evaluate the toxic effects of salicylic Acid (SA) and Paracetamol (PAR) on bean<br>(Phaseolus vulgaris) were investigated. The root length showed significant reduction with an<br>increase in the concentration of PAR in parallel, with an increase in the length of the roots<br>obtained at the highest concentration of SA. On increasing the concentration from PAR and<br>SA, the gradual increase in fresh weight of roots was observed compared to the control. After<br>exposure to the different concentrations, PAR and SA treatments caused damage to the<br>protein synthesis. In addition, a significant stimulation of proline synthesis is recorded after<br>treatment with PAR compared with the value obtained in the presence of SA at the highest<br>concentration. Lipid peroxidation supported by a significant increase in MDA and H 2 O 2<br>levels, particularly for PAR treatments, are also observed. The evaluation of the respiratory<br>activity of the isolated bean roots shows an oxygen consumption related to the PAR<br>concentrations. This consumption is much higher in the presence of SA. Finally, our results<br>show that pharmaceutical products and their residues (such as PAR and SA), released into the<br>environment in large quantities and without treatment, can produce morphological,<br>biochemical and metabolic changes in the roots of non-target plant species such as bean that<br>can seriously disrupt root functioning.</p> ER -